Transgenic Animals Applications Ppt

11 These and chronic models for the evaluation of transgenic animals can express HIV-1 proteins.

Transgenic animals applications ppt. Transgenic animals produced with. Recombinant DNA technology is the ability to combine DNA molecules from different sources into the one molecule. A transgenic animal is one that carries a foreign gene that has been deliberately inserted into its genome.

Transgenic Animals Synthetic modified or other foreign genes can be introduced into animals and plants and the resulting transgenic organisms can be used to study the function of the genes for example by insertional mutagenesis to produce novel products or to serve as animal models for studies of inherited human diseases. DNA Technology Biotechnology The use or alteration of cells or biological molecules for specific applications Transgenics Transgenic changed genes Recombinant DNA DNA from different species mixed together Natural or man-made Whole organisms or cells Possible because the genetic code is universal All life uses the same genetic code ATGC Amplifying DNA Need. 356 have been used as experimental animals for production of transgenic fish.

Let us have a detailed look at the process importance and applications of transgenic animals. Applications Transgenic models for Alzheimer disease amyotrophic lateral sclerosis Huntington disease arthritis muscular dystrophy tumorigenesis hypertension neurodegenerative disorders endocrinological dysfunction coronary disease etc. Transgenic animals are used as tools in research and for the production of recombinant proteins The main applications of transgenic animals are described as followsStudying gene function.

Selection of Fish Species. Several different fish spe-cies including channel catfish common carp goldfish Japanese medaka loach northern pike rainbow trout salmon tilapia walleye and zebrafish for review. Transgenic animals ie engineered to carry genes from other species have the potential to improve human welfare.

Methodology and Applications Transgenic mice. Ful in generating transgenic animals but may have applications as transient gene-expression systems 15. The creations of many transgenic animals were subsequently reported in 1985s 6.

A transgenic animal is animal whose chromosomes have been changed to carry the. Animal egg stage is also developed19 There are Since than many models have developed other models like beta receptor knockout mouse Rosenstiel et al gives summary of 32 transgenic uncoupling protein UCP1 knockout mouseacute murine HIVAN models developed. Foreign genes are inserted into the germ line of the animal so it can be transmitted to the progeny.